Sabtu, 24 Maret 2012

[V811.Ebook] Ebook Free Applied Biopharmaceutics and Pharmacokinetics, by Leon Shargel, Andrew B.C. Yu

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Applied Biopharmaceutics and Pharmacokinetics, by Leon Shargel, Andrew B.C. Yu

Applied Biopharmaceutics and Pharmacokinetics, by Leon Shargel, Andrew B.C. Yu



Applied Biopharmaceutics and Pharmacokinetics, by Leon Shargel, Andrew B.C. Yu

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Applied Biopharmaceutics and Pharmacokinetics, by Leon Shargel, Andrew B.C. Yu

This new edition emphasizes the application and understanding of basic theoretical principles of biopharmaceutics and pharmacokinetics. Now with a second highlight color, this book helps students gain skills in problem solving and includes examples and practice problems and solutions.

  • Sales Rank: #2897748 in Books
  • Published on: 1999-01-01
  • Original language: English
  • Number of items: 1
  • Dimensions: 10.20" h x 1.37" w x 7.60" l,
  • Binding: Hardcover
  • 792 pages

Review
“…useful to pharmaceutical scientists and clinical pharmacists needing to penetrate the sometimes arcane discipline of pharmacokinetic theory.” (The Annals of Pharmacotherapy 2000-03-01)

From the Back Cover
Key Benefit: This book emphasizes the application and understanding of core areas involving bioavailability, population pharmacokinetics, metabolism, and drug delivery. Key Topics: The fourth edition has a new features entitled "practice focused section" that includes a pharmacy practice component with clinical emphasis. Each chapter also has learning problems, and frequently asked questions. Market: Pharmacy students.

About the Author
Leon Shargel is vice president and technical director of the National Association of Pharmaceutical Manufacturers, a trade organization representing generic drug makers. An author of a pharmacy review book, he is also an adjunct professor at the University of Maryland.

Andy Yu, formerly a professor at the Albany College of Pharmacy, is currently with the FDA in Rockville, MD.

Most helpful customer reviews

13 of 16 people found the following review helpful.
Applied Biopharmaceutics and Pharmacokinetics
By Amazon Customer
This book is fantastic! It is the fourth edition of the popular textbook on biopharmaceutics. The authors have maintained the excellent standards of previous editions, by clearly explaining the concepts while keeping mathematical derivations to a minimum. The "practical focus" sections show the application of pharmacokinetics in a clinical setting. A new chapter on targeted drug delivery and newer biotech drugs is very timely and relevant. Overall, this is an excellent book on biopharmaceutics and pharmacokinetics. It is recommended not only for the newcomer, but serves as a valuable reference in any library.

7 of 10 people found the following review helpful.
Not helpful
By A Customer
I used this book as a help while studying for a pharmacokinetics course in pharmacy school. I found it to be of little use for this purpose.
Reading one chapter to learn a concept was not helpful as there was little focus on important details, just a lot of little picky information that really wasn't necessary. And looking up one particular piece of information was even difficult as vague examples and rambling sentences made reading the entire chapter a must.
As a review tool, the problems at the ends of the chapters were not helpful, either. The problems went from too easy to fantastically difficult with no in between.
As a student this wasn't a helpful reference or study tool.

See all 3 customer reviews...

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Selasa, 20 Maret 2012

[X654.Ebook] Ebook One Flew Over the Cuckoo's Nest, by Ken Kesey

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One Flew Over the Cuckoo's Nest, by Ken Kesey

An international bestseller and the basis for the hugely successful film, Ken Kesey's One Flew Over the Cuckoo's Nest is one of the defining works of the 1960s.

In this classic novel, Ken Kesey’s hero is Randle Patrick McMurphy, a boisterous, brawling, fun-loving rebel who swaggers into the world of a mental hospital and takes over. A lusty, life-affirming fighter, McMurphy rallies the other patients around him by challenging the dictatorship of Nurse Ratched. He promotes gambling in the ward, smuggles in wine and women, and openly defies the rules at every turn. But this defiance, which starts as a sport, soon develops into a grim struggle, an all-out war between two relentless opponents: Nurse Ratched, backed by the full power of authority, and McMurphy, who has only his own indomitable will. What happens when Nurse Ratched uses her ultimate weapon against McMurphy provides the story’s shocking climax.

“BRILLIANT!”—Time

“A SMASHING ACHIEVEMENT...A TRULY ORIGINAL NOVEL!”—Mark Schorer

“Mr. Kesey has created a world that is convincing, alive and glowing within its own boundaries...His is a large, robust talent, and he has written a large, robust book.”—Saturday Review

  • Sales Rank: #1678 in Books
  • Color: Multicolor
  • Brand: Signet
  • Published on: 1963-02-01
  • Released on: 1963-02-01
  • Original language: English
  • Number of items: 1
  • Dimensions: 7.52" h x 1.13" w x 4.25" l,
  • Binding: Mass Market Paperback
  • 272 pages
Features
  • Great product!

From Library Journal
Kesey's new introduction to this anniversary edition could very well be the last thing he worked on before shuffling off this mortal coil in 2001. Additionally, 25 sketches he drew while working at a mental institution in the 1950s, the inspiration for the novel, are littered throughout. Critics are divided on the meaning of the book: Is it a tale of good vs. evil, sanity over insanity, or humankind trying to overcome repression amid chaos? Whichever, it is a great read.
Copyright 2002 Reed Business Information, Inc.

Review
"A glittering parable of good and evil." —The New York Times Book Review

"A roar of protest against middlebrow society’s Rules and the Rulers who enforce them." —Time

From the Inside Flap
An international bestseller, Ken Kesey's One Flew Over the Cuckoo's Nest defined the 1960s era of ever-widening perspectives and ominous repressive forces. Full of mischief, insight, and pathos, Kesey's powerful story of a mental ward and its inhabitants probes the meaning of madness, often turning conventional notions of sanity and insanity on their heads.

The tale is chronicled by the seemingly mute Indian patient, Chief Bromden; its hero is Randle Patrick McMurphy, the boisterous, brawling, fun-loving rebel who encourages gambling, drinking, and sex in the ward, and rallies the other patients around him by challenging the dictatorial rule of Big Nurse. McMurphy's defiance -- which begins as a sport -- develops into a grim struggle with the awesome power of the "Combine", concluding with shattering, tragic results. In its unforgettable portrait of a man teaching the value of self-reliance and laughter destroyed by forces of hatred and fear, One Flew Over the Cuckoo's Nest is a classic parable that has left an indelible mark on the literature of our time.

Most helpful customer reviews

176 of 194 people found the following review helpful.
Fabulous and Inspirational
By Hassan Galadari
This novel officially ends the 4-book reading that I had set forth to get my teeth into this summer. I must say, that it truly stands out from anything I had read before it, be it this summer or anytime for that matter. Ken Kesey weaves a tale that is smart, witty, sometimes insane and ultimately tragic. Though the setting is mainly in a mental asylum somewhere in Oregon, this story has a universal appeal to it that can be felt by anyone, anwhere in this world.
R.P. McMurphy is a sane man that, due to a brush with the law, opts for being committed in a mental asylum rather than be incarcerated with hard labor. Upon his entry in the secluded world of the asylum, he strips all the barriers formed and starts laying his own rules, in his own way. This leads to problems with the head honcho of the place. A big, gruesome, and menacingly evil Nurse Ratched, dubbed Big Nurse for her huge frame and even huger bosom. The rollercoaster, that patient McMurphy takes the inmates through, finally leads them to realize the ultimate goal. That man, no matter the situation, can always hold his destiny in his hands. This knowledge, achieved in the end, does not come without a price.
Set in the late 60s, early 70s, One Flew Over the Cuckoo's Nest is a gem of modern literary works that came out at the time. It brought out a wonderfully-made movie, starring Jack Nicholson as McMurphy. The role defined him as an actor to be reckoned with. Though the mavie is seen through the eyes of McMurphy, the novel's perspective looks at things through the eyes of a big half white, half Native American inmate, that acts deaf and dumb in front of the asylum's staff. The narrative, because it is through the eyes of a mental patient, can at times be truly insane. That's where the fun really lies. Kesey works his magic in making us feel the insanity and despair of the patients. He can be funny, in a laugh out loud kind of fashion. He can also be tragic, when you realize what the inmates go through each passing day. The novel is a definitive treatment of the age old abode of individual versus establishment.
This is a very human story, with a lot of suffering and exploration of man's insecurities. It has become a classic that some schools have even recommended as part of their curriculum. Through all the ups and downs of the story, I was, forever inspired and ultimately liberated in mind to finally realize that you can take away a man's life, but never his freedom. The book receives my highest recommendation.

1 of 1 people found the following review helpful.
Plumb Crazy
By Niles Jacobsen
Ken Kesey's "One Flew Over the Cuckoo's Nest" was one of the most powerful books I have ever read. Although the story takes place mainly in a mental hospital, its ramifications can be felt in all of the broader society. The struggles depicted in the various characters, both internally and inter-personally, will give the reader pause and perhaps change your perception on life.

The story at its core encompasses the struggle between the individual (portrayed by Randall McMurphy) and the establishment (Portrayed by nurse Ratched.) It is told through the eyes of the schizophrenic half-Indian known as Chief Bromden. Bromden has pretended to be deaf and dumb for so long that everyone takes this fact for granted. It also allows him to overhear comments from the staff that others would not. The Chief is an interesting choice as narrator, and at times it seemed like he was rambling on about nothing. Unreliable narrators can be a touchy thing, but Kesey is able to navigate his way through the Chief's mind, and in time we find his ramblings have a purpose. He views the establishment as a machine, which he refers to as "the combine." He speaks of fog machines, wires in the walls, and robotic people, and views them as part of the combine. Even the name of the nurse, Ratched, sounds almost like "ratchet," which is a common tool. The Chief sees the struggle between the Big Nurse, as he calls Ratched, and McMurphy, and even though he has a sense right away that McMurphy is different, Bromden doesn't hold out much hope. After all, the combine is a massive machine and the Chief knows what it did to him. Bromden tells McMurphy he "used to be big," but not any more. The Chief's mother, a white woman from town, along with the government, broke down both he and his father and became bigger than both of them put together.

The antagonist is Ratched, an ex-army nurse who rules the ward with an iron fist. She preys on the weaknesses of the patients and attacks them in those areas. She is all about control and power, and over her long career has devised many ways of projecting this with a cold, machine-like efficiency. Ratched has hand picked her staff based on their cruelty and submissiveness. The Chief calls her "The Big Nurse," which reminds me of Orwell's Big Brother, and mentions early on that "The Big Nurse tends to get real put out if something keeps her outfit from running like a smooth, accurate, precision-made machine" (pg 24). Indeed the Chief sees her as a machine, part of the combine who's purpose is to make others small. Ratched represents the oppressive nature and de-humanization present in modern society.

And then there is Randle McMurphy. Sent to the ward from a work farm (because it's "easier" time), McMurphy comes in loud and confident. His singing and laughter are something new for the patients so used to suppressing their emotions. And he is definitely not the kind of patient the mechanical and repressive Nurse Ratched wants. It only takes McMurphy one group session to see Ratched's method of exposing the patient's weakest areas and pecking them into submission. Harding, the subject of the group meetings earlier frenzy, explains that it was all therapeutic. McMurphy, however, gives Harding his perception: "what she is is a ball-cutter. I've seen a thousand of 'em...people who try to make you weak so they can get you to...live like they want you to. And the best way to do this...is to weaken you by gettin' you where it hurts the worst" (pg 56). So McMurphy, ever the gambling man, makes a bet with his fellow patients that he would be able to make Ratched lose her composure, and he accomplished this by using her own tactics against her. As he pulls Bromden and the others out of the "fog" and makes them big again, McMurphy unwittingly becomes the savior of his fellow patients. It did not go un-noticed that the electroshock table was cross-shaped with the patient restrained by the wrists and feet and a "crown" placed over his head. When McMurphy rips Nurse Ratched's tightly starched uniform and exposes her breasts, he is symbolically exposing her hypocrisy and breaking the power she had once wielded over the patients. Chief Bromden's final act of mercy cemented Nurse Ratched's fall as well as giving McMurphy the dignity that he had earned.

Perhaps the largest piece of advice I pulled from this novel is to never let anyone or anything take your individuality. Society in general would like to have everyone fit into the same mold because then the people are easier to predict and control. However, we all need a McMurphy in our lives to show us that we can still be individuals and fit into society. And when The Combine tries to weaken you and make you conform, just throw your head back and laugh like McMurphy, "because he knows you have laugh at the things that hurt you just to keep yourself in balance, just to keep the world from running you plumb crazy" (pg 233).

63 of 70 people found the following review helpful.
Simply Divine
By Jeffrey Leach
Counterculture icon and author Ken Kesey (1935-2001) wrote his first novel, "One Flew Over the Cuckoo's Nest," in 1960. The book was a response to the author's experiences testing mind-altering drugs for the federal government and his later tenure as a nurse's aide in the same facility. In the introduction to the novel, Robert Faggen places this seminal novel in its proper context, arguing that this book incorporates several themes of the 1950's: the Cold War, the plight of the Native Americans, the reliance on psychiatry as a cure all for social problems, and the vestigial remnants of McCarthyism. Even if you could care less about how Kesey's book fits into American cultural history, you could hardly fail to miss the overarching theme of his novel: the tensions between the individual and the state, between those trapped in an industrial society and those who wish to live in freedom. There is a film version of this book starring Jack Nicholson and Louise Fletcher that adequately captures Kesey's stark visions.
The author's tale takes place in a mental asylum at an unknown time. Perhaps this is because time has little importance to the inmates in the facility. The people in this particular ward of the hospital fall into categories of `acute' or `chronic,' depending on whether they have hope of recovery or are irrevocably ill. The days are full of drudgery, an endless round of medications interspersed with playing cards against the background of canned polka music. Everyday the acute patients meet for group therapy that really doubles as a McCarythyesque tattling session. The name of the game is acquiescence to the myriad rules and regulations of the institution. Those inmates who violate the rules earn a trip to the disturbed ward or a quick trip to the electroshock chamber. Repeated disobedience could lead to a lobotomy. Predictably, fear is the perpetual state in which most of the patients live. But with the appearance of a nonconformist named Randle McMurphy, fear starts to give way to a burgeoning hope that life will become better in this hospital.
The narrator of this story is Chief Bromden, a mixed blood Indian who is a patient in the ward. This man spends his days mopping and sweeping the floors while hearing and seeing everything that goes on around him. The Chief fears that something called the `Combine' controls the world. For him, the `Combine' is the machinery that fills the walls and floors of the hospital, constantly spying on and controlling the men in the ward. He believes that those who work in the asylum are actually full of cogs and gears, are part of this giant, controlling machine. Moreover, the staff and the patients believe that Bromden is a deaf mute. He isn't, but Kesey's choice of this Indian as the narrator of unfolding events is a stroke of brilliance. Since no one thinks the Chief can hear or speak, he becomes privy to every activity in the institution. The staff speaks freely around him because they feel they have nothing to worry about. His cleaning duties allow him full access to every area of the floor, including the room where the staff meets to discuss other inmates. You cannot help but like Bromden, and you quickly question whether his observations are truly the ramblings of a madman.
The central figure in Bromden's `Combine' theory is Nurse Ratched, sometimes referred to as `Big Nurse.' This seemingly grandmotherly woman personifies the Chief's fear of control and cold aloofness. Ratched runs the floor from her little glass booth, her hands on the levers of the machinery that controls the lights, the music, the group therapy sessions, and even most of the doctors. Her voice alone controls the destiny of the inmates. Ratched enforces the rules and regulations, and she decides who receives punishment or release. Big Nurse encourages stool pigeons and belittles the patients with implied threats and stony glares, often masked under an ersatz exterior of patience and cheerfulness. With the arrival of McMurphy, Ratched prepares for a battle of wills that by extension is a war between the individual and the state.
Randle McMurphy is a boisterous, tattooed, redheaded troublemaker ducking a sentence on a work farm by acting crazy. Right from the start, McMurphy undermines the rules and regulations of the hospital. He gambles for money, wonders the hall wearing nothing but towels, sings, and challenges Ratched's authority by going to the floor doctor to receive rule waivers. But far, far worse is McMurphy's effect on the other inmates in the institution. His breezy spirit and tenaciousness encourages others to demand changes in the daily routine. Randle is a subversive of the worst type, and Ratched will do anything in her power to slap down this upstart to her fascistic rule. The end of the story seems to mark a significant defeat for the concept of individualism, but if one reads closely it is apparent Kesey keeps the dream of freedom alive however ephemeral it may be.
Although I disagree strongly with Kesey's career as a counterculture mainstay, I loved this book. Everything about it is brilliant, from the characterization to the tight writing style. The Penguin edition even includes pencil sketches of people Kesey drew during his work as a nurse's aide. These haunting sketches add a special dimension to the text. Ultimately, the novel works because of its messages of freedom versus entrapment and the dangers of both conformity and nonconformity to the human soul. I recommend you run, not walk, to get this book.

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Senin, 19 Maret 2012

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  • Sales Rank: #2335200 in Books
  • Published on: 2016-01-05
  • Original language: English
  • Dimensions: 9.00" h x .38" w x 6.00" l,
  • Binding: Paperback
  • 168 pages

About the Author
Haley Lynn Gray is founder and owner of Leadership Girl, a graduate of Duke's Fuqua School of Business, and a serial entrepreneur. In addition to her many business ventures, she is also a wife, mom of four and Girl Scout Leader to four troops. She's also the Troop Cookie Manager for her Girl Scout Troops, with over 15,000 boxes of cookies going through her garage in a typical year. Haley is passionate about helping women achieve their potential and empowers them to overcome obstacles in leadership positions and entrepreneurial ventures. After starting and growing several businesses of her own to success, Haley wanted to provide the benefit of her experiences and expertise to others. She began coaching small business owners so they could achieve their own success. At Leadership Girl, Haley supports entrepreneurs and contributes to their success by offering business building services for small businesses such as: Business Coaching and Strategy Sessions. Whether you want to get a new business off the ground or expand an existing business, Haley is here to help you.

Most helpful customer reviews

0 of 0 people found the following review helpful.
Genius
By Kendrick Shope
Haley is an expert and I love reading this. She's run so many successful businesses and it a joy, not to mention whip smart!

2 of 2 people found the following review helpful.
Get the right attitude for building a business -- not just for women
By Douglas Brown
Here's a good book and an easy read that explains from experience many of the things you'll need to know about to build a company. This book is miles ahead of the "info-product" junk that collages together lists of the top-ten apps you need for this and that or slick schemes for "building a tribe". And, despite the title, it's neither a feminist rant about having to be 10 times better, nor is it a New Age kumbaya story. What it does very well is talk about building a business - not just a solo coaching effort or an internet marketingbscheme but a real business with services and employees. It doesn't go into the simple factual stuff about how to incorporate or how to set up a chart of accounts, which can be researched on line easily enough. Instead it provides the much more valuable service of getting into the mindset you need to have, from the perspective of someone who has done it. For instance, the hiring of staff chapter is about how to interview to get the right person (a very challenging art) rather than just reciting typical fee structures for recruiting companies. If you're a guy, don't let the title scare you off: the feminist parts are neatly packaged into one small chapter that you can skip past, and the rest is well worth the reading. All in all, a refreshing change from offerings that are mostly about how to buy someone's training or marketing program. This book is about keeping your head in the game so you can succeed in your own business.

1 of 1 people found the following review helpful.
So many great tips, I am going to read it again and again!
By Lee Lambert
I loved this book! I am just starting out as a self-published author and the tips and tools are just what I needed to read. The idea of quit hiding and negotiating hit me the most. I am not one to sit there and shout from the rooftops my accomplishments. So that is a really tough hurdle for me to get over, but if I don't talk about my books, no one will ever know about it.

The second, negotiation is extremely hard for me. When I first realized I had a rough time was when I was 19 in the Philippines with my boyfriend. He walked up to a store selling video games and started arguing the price listed until they settled on a price (lower than the listed price.) It was the first time in my life I had really seen that. Since that, I used it more for advocating my grades in college and learning how to negotiate when I went back to Asian countries. I am still not very good at negotiating, but I think in general, that is just not the culture or environment I was raised in.

This book reminded me that it is OK not to accept the first offer and wait it out to see what happens, or hold out for a better offer. I am so thankful I picked up this book.

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Leadership Girl: Empowering Women Entrepreneurs to Achieve Extraordinary Results PDF
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Selasa, 13 Maret 2012

[R582.Ebook] Fee Download Probability, Reliability, and Statistical Methods in Engineering Design, by Achintya Haldar, Sankaran Mahadevan

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Learn the tools to assess product reliability! Haldar and Mahadevan crystallize the research and experience of the last few decades into the most up-to-date book on risk-based design concepts in engineering available. The fundamentals of reliability and statistics necessary for risk-based engineering analysis and design are clearly presented. And with the help of many practical examples integrated throughout the text, the material is made very relevant to today's practice. Key Features
* Covers all the fundamental concepts and mathematical skills needed to conduct reliability assessments.
* Presents the most widely-used reliability assessment methods.
* Concepts that are required for the implementation of risk-based design in practical problems are developed gradually.
* Both risk-based and deterministic design concepts are included to show the transition from traditional to modern design practice.

  • Sales Rank: #1130843 in Books
  • Published on: 1999-11-01
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.55" h x .70" w x 6.32" l, 1.31 pounds
  • Binding: Hardcover
  • 320 pages

From the Back Cover
Learn the tools to assess product reliability! Haldar and Mahadevan crystallize the research and experience of the last few decades into the most up-to-date book on risk-based design concepts in engineering available. The fundamentals of reliability and statistics necessary for risk-based engineering analysis and design are clearly presented. And with the help of many practical examples integrated throughout the text, the material is made very relevant to today's practice. Key Features
* Covers all the fundamental concepts and mathematical skills needed to conduct reliability assessments.
* Presents the most widely-used reliability assessment methods.
* Concepts that are required for the implementation of risk-based design in practical problems are developed gradually.
* Both risk-based and deterministic design concepts are included to show the transition from traditional to modern design practice.

Most helpful customer reviews

0 of 0 people found the following review helpful.
Expensive, not exhaustive
By Zhe yang
Expensive to buy. Does not contain everything, like more advanced topics of reliability design, such as Monte Carlo, Fault Tree, Structural Reliability etc etc. Has good amount of examples.

0 of 0 people found the following review helpful.
Great book, especially if you're getting started in Probabilistic ...
By Ricardo Cruz Lozano
Great book,especially if you're getting started in Probabilistic Analysis.

0 of 0 people found the following review helpful.
Four Stars
By Francisco Villegas
The book in general is good but I think it is expensive.

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From Authors Preface: This book represents my effort to synthesize in as concise a statement as possible the ideas that have permeated my writing in the filed of art education during the past decade. Understanding how people develop their ability to respond to and create visual form is one of utmost complexity. (Description by http-mart)

  • Sales Rank: #829104 in Books
  • Published on: 1972-06
  • Ingredients: Example Ingredients
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.75" h x 8.50" w x .75" l,
  • Binding: Paperback
  • 352 pages

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0 of 0 people found the following review helpful.
Rare treasure
By Clifford
This is iconic work from a great educator. This is a rare out-of print book. I'm glad I found it!

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Kamis, 08 Maret 2012

[F386.Ebook] Download Mathematics for the Clinical Laboratory, 2e 2nd Edition

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Mathematics for the Clinical Laboratory, 2eDoucette MS MT(ASCP) CLS(NCA), Lorraine J.

  • Sales Rank: #17209660 in Books
  • Published on: 2010
  • Number of items: 2
  • Binding: Paperback

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Minggu, 04 Maret 2012

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  • Sales Rank: #3716200 in Books
  • Published on: 2007-01-01
  • Format: Import
  • Original language: English
  • Binding: Paperback
  • 64 pages

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